Selection for increased voluntary wheel-running affects behavior and brain monoamines in mice
نویسندگان
چکیده
منابع مشابه
Selection for increased voluntary wheel-running affects behavior and brain monoamines in mice.
Selective-breeding of house mice for increased voluntary wheel-running has resulted in multiple physiological and behavioral changes. Characterizing these differences may lead to experimental models that can elucidate factors involved in human diseases and disorders associated with physical inactivity, or potentially treated by physical activity, such as diabetes, obesity, and depression. Herei...
متن کاملArtificial selection for increased wheel-running behavior in house mice.
Replicated within-family selection for increased voluntary wheel running in outbred house mice (Mus domesticus; Hsd:ICR strain) was applied with four high-selected and four control lines (10 families/line). Mice were housed individually with access to activity wheels for a period of 6 days, and selection was based on the mean number of revolutions run on days 5 and 6. Prior to selection, herita...
متن کاملSelection for high voluntary wheel-running increases speed and intermittency in house mice (Mus domesticus).
In nature, many animals use intermittent rather than continuous locomotion. In laboratory studies, intermittent exercise regimens have been shown to increase endurance compared with continuous exercise. We hypothesized that increased intermittency has evolved in lines of house mice (Mus domesticus) that have been selectively bred for high voluntary wheel-running (wheel diameter 1.12 m) activity...
متن کاملBody temperatures of house mice artificially selected for high voluntary wheel-running behavior: repeatability and effect of genetic selection.
We studied rectal body temperatures of house mice (Mus domesticus) that had been artificially selected for high voluntary wheel running.1. At generation 17, mice from the four replicate selected lines ran, on average, 2.5-times as many revolutions/day as did mice from the four random-bred control lines.2. During the day, repeatability of individual differences in body temperature measured 4 day...
متن کاملBody temperatures of house mice arti®cially selected for high voluntary wheel-running behavior: repeatability and eect of genetic selection
We studied rectal body temperatures of house mice (Mus domesticus ) that had been arti®cially selected for high voluntary wheel running. 1. At generation 17, mice from the four replicate selected lines ran, on average, 2.5-times as many revolutions/day as did mice from the four random-bred control lines. 2. During the day, repeatability of individual dierences in body temperature measured 4 da...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brain Research
سال: 2013
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2013.01.033